GSK and Ionis Pharmaceuticals report functional cure rates for hepatitis B drug
- Reports
- 12
- Developments
- 4
- Repetition
- 67%
New informationRepeats or wire copies
What happened
GSK and Ionis Pharmaceuticals reported pivotal Phase 3 results for bepirovirsen, a drug for chronic hepatitis B. In trials B-Well 1 and B-Well 2, 233 of 1,220 treated patients achieved a functional cure, compared to none in the placebo group. The drug is currently under fast-track review by the U.S. Food and Drug Administration, with a decision expected in October.
Why it matters
The drug works by binding to hepatitis B's genetic components, suppressing viral replication, and stimulating the immune system. Achieving a functional cure represents a major step in treating chronic hepatitis B, which can cause liver cancer or liver failure.
From fox4news.com, wokv.com
Who's involved
- GSKCo-developed the bepirovirsen drug for hepatitis B
- Ionis PharmaceuticalsCo-developed the bepirovirsen drug for hepatitis B
How it developed
Newest first. Tap a step to see who reported it.GSK and Ionis partner on bepirovirsen development, trading on Nasdaq.1 source
GSK and Ionis Pharmaceuticals announced the co-development of the bepirovirsen drug for hepatitis B.1 source
Findings on the co-developed bepirovirsen drug were presented at a scientific meeting in Barcelona.1 source
Findings on the co-developed bepirovirsen drug were presented in Barcelona.1 source
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The entities involved
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GSK
British multinational pharmaceutical and biotechnology company
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Ionis Pharmaceuticals
American pharmaceutical company
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Nasdaq
American fully electronic stock exchange