TGA removes Andrographis paniculata ingredient due to severe allergic reactions

The Australian Therapeutic Goods Administration (TGA) removed Andrographis paniculata from its list of permitted ingredients for new listed medicines, effective September 17, 2026. This decision followed years of safety monitoring and ongoing reports of severe allergic reactions, including anaphylaxis. By December 31, 2025, the TGA had received 287 reports of anaphylaxis associated with Andrographis-containing medicines.

This regulatory action impacts the market for herbal and traditional medicine ingredients in Australia. Andrographis is commonly used in supplements and traditional medicine to relieve symptoms of the common cold, flu, and mild URTI. The removal restricts the availability of this specific herbal component for new medicinal products.